Methazolamide
From Wikipedia, the free encyclopedia
 |
|
|
Methazolamide
|
|
| Systematic (IUPAC) name | |
| N-(3-methyl-5-sulfamoyl-3H- 1,3,4-thiadiazol-2-ylidene) ethanamide | |
| Identifiers | |
| CAS number | 554-57-4 |
| ATC code | S01EC05 |
| PubChem | 4100 |
| DrugBank | APRD00740 |
| Chemical data | |
| Formula | C5H8N4O3S2 |
| Mol. weight | 236.274 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 55% |
| Metabolism | ? |
| Half life | 14 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status |
℞-only(US) |
| Routes | Oral |
Methazolamide is a carbonic anhydrase inhibitor.
[edit] References
- Iyer G, Bellantone R, Taft D (1999). "In vitro characterization of the erythrocyte distribution of methazolamide: a model of erythrocyte transport and binding kinetics.". J Pharmacokinet Biopharm 27 (1): 45-66. PMID 10533697.
- RxList. Neptazane. Retrieved on August 20, 2006.
- Shirato S, Kagaya F, Suzuki Y, Joukou S (1997). "Stevens-Johnson syndrome induced by methazolamide treatment.". Arch Ophthalmol 115 (4): 550-3. PMID 9109770.
- Skorobohach B, Ward D, Hendrix D (2003). "Effects of oral administration of methazolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs.". Am J Vet Res 64 (2): 183-7. PMID 12602587.
 |
This medical article is a stub. You can help Wikipedia by expanding it. |
| Antiglaucoma preparations and miotics (S01E) edit | ||
|---|---|---|
| Sympathomimetics: |
Apraclonidine, Brimonidine, Clonidine, Dipivefrine, Epinephrine |
|
| Parasympathomimetics: |
Aceclidine, Acetylcholine, Carbachol, Demecarium, Echothiophate, Fluostigmine, Neostigmine, Paraoxon, Physostigmine, Pilocarpine |
|
| Carbonic anhydrase inhibitors: |
Acetazolamide, Brinzolamide, Diclofenamide, Dorzolamide, Methazolamide |
|
| Beta blocking agents: |
Befunolol, Betaxolol, Carteolol, Levobunolol, Metipranolol, Timolol |
|
| Prostaglandin analogues: |
Bimatoprost, Latanoprost, Travoprost, Unoprostone |
|
| Other agents: |
Dapiprazole, Guanethidine |
|
