MERRF syndrome
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ICD-10 | G31.8 | |
---|---|---|
ICD-9 | 277.87 | |
OMIM | 545000 | |
DiseasesDB | 30794 | |
MeSH | C05.651.460.620.530 |
MERRF syndrome (or Myoclonus with Epilepsy and with Ragged Red Fibers) is a mitochondrial disease involving the following characteristics:
- progressive myoclonic epilepsy
- clumps of diseased mitochondria accumulate in the subsarcolemmal region of the muscle fiber and appear as "ragged-red fibers" when muscle is stained with modified Gomori trichrome stain
- short stature