Mathias Ham House
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- For the 17th century mansion in the United Kingdom, see Ham House, London.
The Mathias Ham House is a 19th century house in Dubuque, Iowa that is on the National Register of Historic Places. It is located at the intersection of Shiras and Lincoln Ave in Dubuque.
The house was built for local businessman Mathias Ham in 1856. The architect was John Rague, who had designed the original capitol buildings of Illinois and Iowa. He designed the house in the Italian Villa style.
The building has been restored, and is a museum showcasing life during the Antebellum period. The house contains American and European furnishings from that period. Also on the site is a log cabin which is considered the oldest building in Iowa.