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Maria Manuela of Portugal
Portuguese royalty
House of Aviz
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| John I |
| Children |
| Infante Duarte (future Edward I) |
| Infante Pedro, Duke of Coimbra |
| Henry the Navigator (Infante Henrique, Duke of Viseu) |
| Infanta Isabel, Duchess of Burgundy |
| Infante João |
| Infante Fernando, the Saint Prince |
| Afonso, Duke of Braganza (illegitimate) |
| Beatriz, Countess of Arundel (illegitimate) |
| Grandchildren include |
| Infanta Isabel of Coimbra, Queen of Portugal |
| Edward |
| Children |
| Infante Afonso (future Afonso V) |
| Infante Fernando, Duke of Viseu |
| Infanta Leonor, Holy Roman Empress |
| Infanta Catarina |
| Infanta Joana, Queen of Castile |
| Grandchildren include |
| Infante Manuel, Duke of Beja (future Manuel I) |
| Infanta Leonor of Viseu, Queen of Portugal |
| Afonso V |
| Children include |
| Blessed Joana, Crown Princess of Portugal |
| Infante João (future John II) |
| John II |
| Afonso, Crown Prince of Portugal |
| Jorge, Duke of Coimbra (illegitimate) |
| Manuel I |
| Children include |
| Miguel da Paz, Crown Prince of Spain and Portugal |
| Infante João (future John III) |
| Infanta Isabel, Holy Roman Empress |
| Infanta Beatriz, Duchess of Savoy |
| Infante Luís, Duke of Beja |
| Infante Fernando, Duke of Guarda and Trancoso |
| Infante Cardinal Afonso |
| Infante Cardinal Henrique (future Henry I) |
| Infante Duarte, Duke of Guimarães |
| Infanta Maria |
| Grandchildren include |
| Philip II of Spain (future Philip I of Portugal) |
| António, Prior of Crato (future Anthony I) (illegitimate) |
| Infanta Maria of Guimarães, Duchess of Parma and Piacenza |
| Infanta Catarina of Guimarães, Duchess of Braganza |
| Great-Grandchildren include |
| Teodósio II, Duke of Braganza |
| Rannuccio Farnense of Parma |
| Great-Great-Grandchildren include |
| John II, Duke of Braganza (future John IV of Portugal) |
| John III |
| Children include |
| Infanta Maria Manuela, Princess of Asturias |
| João, Crown Prince of Portugal |
| Grandchildren include |
| Infante Sebastião (future Sebastian I) |
| Carlos, Prince of Asturias |
| Sebastian |
| Henry |
| Anthony (disputed king) |
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Maria Manuela of Portugal (1527–1545, pron. IPA: [mɐ'ɾiɐ mɐnu'ɛlɐ]; English: Mary Emmanuella) as a Portuguese Princess daughter of King John III of Portugal and his wife Catherine of Habsburg. She is also known as Maria Manuela. She was Princess Consort of Asturias.
Maria was born in Coimbra on October 15, 1527 and was one of the few children of John III to survive childhood. She married with Prince Philip of Asturias (future Philip II of Spain and I of Portugal) and was the mother of Prince Carlos, a deformed child who was heir of the Spanish crown.
Maria died soon after she gave birth to Don Carlos of Spain (1545-1568) on August 12, 1545 in Valladolid, Spain.
