Marchiafava-Bignami disease

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Marchiafava-Bignami disease
Classifications and external resources
DiseasesDB 31494
eMedicine neuro/204 

Marchiafava-Bignami disease is a progressive neurological disease characterized by corpus callosum demyelination and necrosis and subsequent atrophy. It is associated with chronic alcoholism. It was first described in 1903 by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker.

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