Macrocytosis
From Wikipedia, the free encyclopedia
| ICD-10 | D75.8 |
|---|---|
| ICD-9 | 289.89 |
| DiseasesDB | 7688 |
| eMedicine | med/1381 |
Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).
[edit] Causes
Most commonly this aetiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include:
- Vitamin B12 or folate deficiency
- hypothyroidism
- reticulocytosis
- liver disease
- myeloproliferative disease
[edit] Complications
No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology.
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