Lymphoblast

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Lymphoblast
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Lymphoblast

Lymphoblasts are immature lymphocyte which typically differentiate to form normal lymphocyte but which proliferate uncontrollably in leukemia. In speaking about leukemia, "blast" is the short name used for lymphoblasts.

The National Cancer Institute (NCI) definition, contradicts this definition. However, their defnition seems to be of activated B-cell.

The Chronic Lymphocytic Leukemia Research Consortium defines a lymphoblast as "A lymphocyte that has become larger after being stimulated by an antigen. Lymphoblasts look like immature lymphocytes, and were once thought to be precursor cells."[1]

[edit] Additional images

Blood cell lineage

They are 2.5 nanometers in size

[edit] References

  1. ^ http://cll.ucsd.edu/glossaryl.htm

[edit] External links

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Blood - Blood plasma
Pluripotential hemopoietic stem cells | Red blood cells (Reticulocyte, Normoblast) | White blood cells
Lymphoid
T cells (Cytotoxic, Helper, Regulatory T cells, Natural Killer T cells) | B cells (Plasma cells & Memory B cells) | Natural killer cells
Myeloid
Granulocytes (Neutrophil, Eosinophil, Basophil) | Mast cell precursors | Monocytes (Histiocyte, Macrophages, Dendritic cells, Langerhans cells, Microglia, Kupffer cells, Osteoclasts) | Megakaryoblast | Megakaryocyte | Platelets
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