Loxapine

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Loxapine chemical structure
Loxapine
Systematic (IUPAC) name
 ?
Identifiers
CAS number 1977-10-2
ATC code N05AH01
PubChem 3964
DrugBank APRD00574
Chemical data
Formula C18H18ClN3O
Mol. weight 327.808 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life Oral-4 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Loxapine (sold as Loxapac®, Loxitane®) is a typical antipsychotic medication, used primarily in the treatment of schizophrenia. It is a member of the dibenzodiazepine family and structurally related to clozapine. Several researchers have argued that Loxapine may behave as an atypical antipsychotic PMID 10340686

[edit] Side effects

Side effects include tardive dyskinesia, neuroleptic malignant syndrome, extrapyramidal side effects, tremor and sedation.


Antipsychotics (N05A) edit
Phenothiazine typical antipsychotics:

Chlorpromazine, Fluphenazine, Mesoridazine, Perphenazine, Prochlorperazine, Promazine, Thioridazine, Trifluoperazine

Other typical antipsychotics:

Chlorprothixene, Droperidol, Flupentixol, Haloperidol, Loxapine, Molindone, Pimozide, Sulforidazine, Thiothixene

Atypical antipsychotics:

Abilify, Amisulpride, Aripiprazole, Clozapine, Olanzapine, Quetiapine, Risperidone/Paliperidone, Sertindole, Sulpiride, Ziprasidone, Zotepine