List of notable genes
From Wikipedia, the free encyclopedia
This is a list of notable human genes or genetic variations.
Note: this does not attempt to be an exhausive list of genes, of which there are tens of thousands for humans alone: this is intended to be a list of genes which are particularly notable in scientific research or in their role in relation to disease, or have featured in a recent significant research paper or news story.
| Name | Locus | Full/Alternate name | Associated Disease(s)/other notes | Reference |
| ALB | 4q11-q13 | albumin | -- | ALB |
| APC | 5q21-q22 | ADENOMATOUS POLYPOSIS OF THE COLON | Familial adenomatous polyposis | APC |
| APECED | 21q22.3 | AUTOIMMUNE POLYENDOCRINOPATHY-CANDIDIASIS-ECTODERMAL DYSTROPHY | -- | APECED |
| APP | 21q21 | Amyloid precursor protein | Alzheimer's Disease | APP |
| ASPM | 1q31 | Abnormal Spindle-like, Microcephaly-associated | microcephaly | ASPM |
| Bcl-2 | 18q21.3 | B-CELL CLL/LYMPHOMA 2 | -- | Bcl-2 |
| BDNF | 11p13 | Brain-derived neurotrophic factor | -- | BDNF |
| BNP | 1p36.2 | Brain Natriuretic Peptid | -- | BNP |
| BRCA1 | 17q21 | Breast Cancer 1 | breast cancer | BRCA1 |
| BRCA2 | 13q12-13 | Breast Cancer 2 | breast cancer | BRCA2 |
| CCR5 | 3p21 | - | Resistance to Infection | CCR5 |
| CD23 | 19p13.3 | - | -- | CD23 |
| CD34 | 1q32 | - | -- | CD34 |
| CD4 | 12pter-p12 | - | -- | CD4 |
| CD8 | 2p12 | - | -- | CD8 |
| CDK2 | 12q13 | - | -- | CDK2 |
| CFTR | 7q31.2 | - | Cystic Fibrosis | CFTR |
| CREB | 2q32.3-q34 | - | -- | CREB |
| CRH | 8q13 | - | -- | CRH |
| CXCR4 | 2q21 | CHEMOKINE, CXC MOTIF, RECEPTOR 4; CXCR4 | -- | CXCR4 |
| DAP | 5p15.2 | - | -- | DAP |
| DHFR | 5q11.2-q13.2 | - | -- | DHFR |
| E2F | 20q11.2 | - | -- | E2F |
| FOS | 14q24.3 | - | -- | FOS |
| Fyn | 6q21 | - | -- | Fyn |
| GAS | 17q21 | - | -- | GAS |
| HFE gene | 6p21.3 | - | -- | HFE |
| Id3 | 1p36.13-p36.12 | - | -- | Id3 |
| IL-2 | 4q26-q27 | Interleukin 2 | -- | IL2 |
| IL-10 | 1q31-q32 | Interleukin 10 | -- | IL-10 |
| IL-12 | 3p12-q13.2; 5q31.1-q33.1 | Interleukin 12 | -- | IL-12 |
| KRT14 | 17q12-q21 | - | -- | KRT14 |
| KRT5 | 12q13 | - | -- | KRT5 |
| LAT | 16p11.2 | - | -- | LAT |
| LCK | 1p35-p34.3 | - | -- | LCK |
| LEP | 7q31.3 | - | -- | LEP |
| LIF | 22q12.1-q12.2 | - | -- | LIF |
| MCM6 | 2q21 | minichromosome maintenance deficient 6 | lactose intolerance | MCM6 |
| MYH7 | 14q12 | myosin | Hypertrophic cardiomyopathy | MYH7 |
| MyoD | 11p15.4 | MYOGENIC DIFFERENTIATION ANTIGEN 1 | -- | MyoD |
| OSM | 22q12.1-q12.2 | - | -- | OSM |
| PGL2 | 11q13.1 | - | -- | PGL2 |
| PIP | 7q32-q36 | - | -- | PIP |
| PKC | 16p11.2-q12.1 | - | -- | PKC |
| Zbtb7 (Pokémon gene) | 19p13.3 | - | -- | gene Pokémon gene |
| RHO | 3q21-q24 | - | -- | RHO |
| Rox | 17p13.3 | - | -- | Rox |
| SDHB | 1p36.1-p35 | - | Pheochromocytoma/Paraganglioma | SDHB |
| SDHC | 1q21 | - | -- | SDHC |
| SDHD | 11q23 | - | Paraganglioma | SDHD |
| SRY | Yp11.3 | Testis determining factor | Swyer syndrome | SRY |
| VMAT2 | 10q25 | Vesicular Monoamine Transporter | -- | VMAT2 |
