Leuckart reaction
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The Leuckart reaction is the chemical reaction of ammonium salts of formic acid with aldehydes (or ketones) to form amines by reductive amination.
In addition to ammonia, primary and secondary amines are also successful.
When excess formic acid is used, the reaction is called the Leuckart-Wallach reaction.
[edit] References
- ↑ Leuckart, R. Ber. 1885, 18, 2341.
- ↑ deBenneville, P. L.; Macartney, J. H. J. Am. Chem. Soc. 1950, 72, 3073 - 3075. (DOI:10.1021/ja01163a074)
- ↑ Wallach, O. Ann. 1892, 272, 99.
- ↑ Moore Organic Reactions 1949, 5, 301. (Review)
