Lecithin-cholesterol acyltransferase
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lecithin-cholesterol acyltransferase
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| Identifiers | |
| Symbol(s) | LCAT |
| Entrez | 3931 |
| OMIM | 606967 |
| RefSeq | NM_000229 |
| UniProt | P04180 |
| Other data | |
| EC number | 2.3.1.43 |
| Locus | Chr. 16 q22.1 |
Lecithin-cholesterol acyltransferase (LCAT, also called phosphatidylcholine-sterol O-acyltransferase) is an enzyme which converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol) which is then sequestered into the core of a lipoprotein particle eventually making the newly synthesized HDL spherical. The enzyme is bound to high-density lipoproteins (HDLs) and low-density lipoproteins in the blood plasma
[edit] See also
[edit] References
- Dobiásová M, Frohlich J (1999). "Advances in understanding of the role of lecithin cholesterol acyltransferase (LCAT) in cholesterol transport.". Clin Chim Acta 286 (1-2): 257-71. PMID 10511297.
[edit] External links
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