Latanoprost

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Latanoprost
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pentyl) -cyclopentyl] hept-5-enoate
Identifiers
CAS number	130209-82-4
ATC code	S01EE01
PubChem	60798
DrugBank	APRD01065
Chemical data
Formula	C26H40O5
Mol. weight	432.593 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	17 minutes
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Topical (eye drops)

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes. It is also known by the brand name of Xalatan Op manufactured by Pfizer.

Possible side effects:

• May cause blurred vision;
• May cause eyelid redness;
• May permanently darken eyelashes;
• May cause eye discomfort;
• May eventually cause permanent darkening of the iris to brown (heterochromia);
• May cause a temporary burning sensation during use.
• May cause thickening of the eyelashes.
• Rarely, herpes simplex keratitis.

[edit] External links

• Xalatan (manufacturer's website)

Antiglaucoma preparations and miotics (S01E) edit
Sympathomimetics:	Apraclonidine, Brimonidine, Clonidine, Dipivefrine, Epinephrine
Parasympathomimetics:	Aceclidine, Acetylcholine, Carbachol, Demecarium, Echothiophate, Fluostigmine, Neostigmine, Paraoxon, Physostigmine, Pilocarpine
Carbonic anhydrase inhibitors:	Acetazolamide, Brinzolamide, Diclofenamide, Dorzolamide, Methazolamide
Beta blocking agents:	Befunolol, Betaxolol, Carteolol, Levobunolol, Metipranolol, Timolol
Prostaglandin analogues:	Bimatoprost, Latanoprost, Travoprost, Unoprostone
Other agents:	Dapiprazole, Guanethidine