Karyopherin
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Karyopherins are a group of proteins involved in transporting molecules through the nuclear pores of the nuclear envelope.
Karyopherins, which may act as importins or exportins, are part of the Importin-β super-family which all share a similar three-dimensional structure.
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[edit] Cycle
e.g.
- importin beta + adapter + cargo protein (cytoplasm)-->(karyoplasm)
- importin beta + adapter + Ran-GTP (karyoplasm)-->(cytoplasm)
- Ran-GTP --> Ran-GDP + P