Talk:Kaguya

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[edit] Surety

I am unsure of the veracity of these statements:

This is not a cloned animal because cells from two individuals are used

and

the process used starts with genetically modified mice

First, as far as I have read, there is nothing that says that the cells came from different individuals, only that they were different cells, one taken immaturely and the other taken later. Nonetheless, the processes involved in meiosis would still ensure that it was not a clone.

Second, the mice themselves are not genetically modified, only the eggs — as far as I have read.

-moogle 05:15, 22 Apr 2005 (UTC)

Disambiguation here?

[edit] Modified eggs?

I have read the original paper published in Nature magazine. As far as I remember 2 individuals were used, one was mutant and other one normal. So they took premature egg from young mutant and mature egg from normal adult mouse. I am not sure how do you mean eggs can be mofified (dna of eggs)? They created modified animal that produced modified eggs...

If they used 2 normal animals placenta wouldnt develop properly because of paternal and maternal imprints. So I wondered if someone can tell me, is it theoretically possible to create normal individual by gene therapy which means silencing matriline and amplifying paternally expressed genes without changing their DNA, and can those offspring be fertile?

Thanks