Interleukin 30

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Interleukin 27
Identifiers
Symbol(s) IL27 , IL30, p28
Entrez 246778
OMIM 608273
RefSeq NM_145659
UniProt Q6P676
Other data
Locus Chr. 16 p11


Interleukin-30 (IL-30) is a protein with a molecular weight of 28 Kilodaltons that forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus is sometimes called IL27-p28. The second chain of IL-27 is a molecule called Epstein-Barr induced gene-3 (EBI3). IL-30 is a member of the long-chain, 4-helix bundle family of cytokines, making it structurally similar to IL-6.[1] This gene for this molecule is now officially called IL-27 under HGNC guidelines.[2]


[edit] References

  1. ^ S. Pflanz et al., IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity Volume, 2002, 16, pages 779-790.
  2. ^ http://www.gene.ucl.ac.uk/nomenclature/data/get_data.php?hgnc_id=19157



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Interleukins edit

IL-1 | IL-2 | IL-3 | IL-4 | IL-5 | IL-6 | IL-7 | IL-8 | IL-9 | IL-10 | IL-11 | IL-12 | IL-13 | IL-14 | IL-15 | IL-16 | IL-17 | IL-18 | IL-19 | IL-20 | IL-21 | IL-22 | IL-23 | IL-24 | IL-25 | IL-26 | IL-27 | IL-28 | IL-29 | IL-30 | IL-31 | IL-32 | IL-33 |
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