Interleukin 20

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Interleukin 20
Identifiers
Symbol(s) IL20 , ZCYTO10, IL10D
Entrez 50604
OMIM 605619
RefSeq NM_018724
UniProt Q9NYY1
Other data
Locus Chr. 1 q32


Interleukin-20 (IL-20) is a protein belonging to the IL-10 family of cytokines. IL-20 is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells. [1]


[edit] References

  1. ^ Rich, B.E. Kupper, T.S., Interleukin 20. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2006, Volume 5, Number 3, pages 243-250.



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Interleukins edit

IL-1 | IL-2 | IL-3 | IL-4 | IL-5 | IL-6 | IL-7 | IL-8 | IL-9 | IL-10 | IL-11 | IL-12 | IL-13 | IL-14 | IL-15 | IL-16 | IL-17 | IL-18 | IL-19 | IL-20 | IL-21 | IL-22 | IL-23 | IL-24 | IL-25 | IL-26 | IL-27 | IL-28 | IL-29 | IL-30 | IL-31 | IL-32 | IL-33 |
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