Interleukin 19


Crystal structure of human IL-19
Interleukin 19
Identifiers
Symbol(s)	IL19 , MDA1, ZMDA1, IL-10C
Entrez	29949
OMIM	605687
RefSeq	NM_153758
UniProt	Q9UHD0
PDB	1N1F
Other data
Locus	Chr. 1 q32.2

Interleukin-19 is a cytokine that belongs to the IL-10 family of cytokines along with several other interleukins including IL-10, IL-20, IL-22, IL-24, IL-26, and several virus-encoded cytokines. It signals through the same cell surface receptor (IL-20R) that is used by IL-20 and IL-24. The IL-19 gene is expressed in resting monocytes and B cells. It is up-regulated in monocytes following stimulation with granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide.^[1]

[edit] References

^ Chang, C. et al., Crystal Structure of Interleukin-19 Defines a New Subfamily of Helical Cytokines. Journal of Biological Chemistry, 2003, Volume 278, pages 3308-3313.

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Interleukins edit
IL-1 \| IL-2 \| IL-3 \| IL-4 \| IL-5 \| IL-6 \| IL-7 \| IL-8 \| IL-9 \| IL-10 \| IL-11 \| IL-12 \| IL-13 \| IL-14 \| IL-15 \| IL-16 \| IL-17 \| IL-18 \| IL-19 \| IL-20 \| IL-21 \| IL-22 \| IL-23 \| IL-24 \| IL-25 \| IL-26 \| IL-27 \| IL-28 \| IL-29 \| IL-30 \| IL-31 \| IL-32 \| IL-33 \|