Interleukin 15
From Wikipedia, the free encyclopedia
Interleukin 15
|
|
Identifiers | |
Symbol(s) | IL15 |
Entrez | 3600 |
OMIM | 600554 |
RefSeq | NP_751914 |
UniProt | P40933 |
Other data | |
Locus | Chr. 4 q31 |
Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces cell proliferation of natural killer cells; cells of the innate immune system whose principal role is to kill virally infected cells.
Also worth mentioning is the fact that maintenance of memory cells does not appear to require persistance of the original antigen; instead, survival signals for memory lymphocyes are provided by cytokines such as IL-15.