Idoxuridine

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Idoxuridine
Systematic (IUPAC) name
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]- 5-iodo-pyrimidine-2,4-dione
Identifiers
CAS number	54-42-2
ATC code	D06BB01 J05AB02, S01AD01
PubChem	5905
DrugBank	APRD00504
Chemical data
Formula	C9H11N2IO5
Mol. weight	354.099 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Idoxuridine is an anti-herpesvirus antiviral drug.

[edit] External links

• Seth A, Misra A, Umrigar D (2004). "Topical liposomal gel of idoxuridine for the treatment of herpes simplex: pharmaceutical and clinical implications.". Pharm Dev Technol 9 (3): 277-89. PMID 15458233.
• Otto S. "Radiopharmaceuticals (Strontium 89) and radiosensitizers (idoxuridine).". J Intraven Nurs 21 (6): 335-7. PMID 10392098.
• Fauth E, Zankl H (1999). "Comparison of spontaneous and idoxuridine-induced micronuclei by chromosome painting.". Mutat Res 440 (2): 147-56. PMID 10209337.

Antivirals (primarily J05A, also S01AD and D06BB) edit

Anti-herpesvirus agents   Aciclovir, Cidofovir, Docosanol, Famciclovir, Fomivirsen, Foscarnet, Ganciclovir, Idoxuridine, Penciclovir, Trifluridine, Tromantadine, Valaciclovir, Valganciclovir, Vidarabine Anti-influenza agents Amantadine, Oseltamivir, Peramivir, Rimantadine, Zanamivir   Antiretroviral drugs   NRTIs Abacavir, Didanosine, Emtricitabine, Lamivudine, Stavudine, Zalcitabine, Zidovudine NtRTIs   Tenofovir NNRTIs   Efavirenz, Delavirdine, Nevirapine PIs Amprenavir, Atazanavir, Darunavir, Fosamprenavir, Indinavir, Lopinavir, Nelfinavir, Ritonavir, Saquinavir, Tipranavir Fusion inhibitors Enfuvirtide   Other antiviral agents Adefovir, Fomivirsen, Imiquimod, Inosine,Interferon, Podophyllotoxin, Ribavirin, Viramidine