Idebenone

From Wikipedia, the free encyclopedia

Idebenone chemical structure
Idebenone
Systematic (IUPAC) name
2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-
cyclohexa-2,5-diene-1,4-dione
Identifiers
CAS number 58186-27-9
ATC code N06BX13
PubChem 3686
Chemical data
Formula C19H30O5 
Mol. weight 338.439 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Idebenone (pronounced eye-deb-eh-known) is an organic compound of the quinone family and promoted commercially as a synthetic analog of Coenzyme Q10 (CoQ10).

Idebenone is claimed to have properties similar to CoQ10 in its antioxidant properties. CoQ10 is one of life's most essential biochemicals, hence its title "ubiquinone" (ubi=ubiquitous).

Idebenone is different from Coenzyme Q10 in one very important way. During a hypoxic (low oxygen) condition, CoQ10 can switch function from an anti-oxidizing to an auto-oxidizing process. This auto-oxidation rapidly produces free radicals which damage the tissues of the body.

Idebenone is said to perform the same functions as CoQ10 without the risk of an auto-oxidation reaction.

Idebenone is said to promote NGF (nerve growth factor) in the brain. It appears to reduce tinnitus (ringing in the ears). Idebenone has also been used in topical applications to treat wrinkles.

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Stimulants - edit

Adrafinil, Armodafinil, Caffeine, Modafinil, Nicotine

Sympathomimetic amines (R01, A08, and others) edit

Aminorex, Amphetamine, Benzylpiperazine, Cathinone, CFT, Chlorphentermine, Clobenzorex, Cocaine, Cyclopentamine, Diethylpropion, Ephedrine, Fenfluramine, Mazindol, 4-Methyl-aminorex, Methylone, Methylphenidate, Pemoline, Phendimetrazine, Phenmetrazine, Phentermine, Phenylephrine, Propylhexedrine, Pseudoephedrine, Sibutramine, Synephrine
See also amphetamines
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