Ibutilide

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Ibutilide
Systematic (IUPAC) name
N-[4-[4-(ethyl-heptyl-amino)- 1-hydroxy-butyl]phenyl] methanesulfonamide
Identifiers
CAS number	122647-32-9
ATC code	C01BD05
PubChem	60753
DrugBank	APRD01025
Chemical data
Formula	C20H36N2O3S
Mol. weight	384.578 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	40%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Ibutilide (ibutilide fumarate) is a class III antiarrhythmic agent. It is associated with an extremely high rate of adverse effects, including torsades de pointes. It is not licensed for use in the UK, but is still available in the U.S.

Antiarrhythmic agents (C01B)edit
class Ia:	Ajmaline, Disopyramide, Prajmaline, Procainamide, Quinidine, Sparteine
class Ib:	Aprindine, Lidocaine, Mexiletine, Tocainide
class Ic:	Encainide, Flecainide, Lorcainide, Moricizine, Propafenone
class II:	Propranolol, Metoprolol, Nadolol, Atenolol, Acebutolol, Pindolol, Sotalol see Beta blockers (C07)
class III:	Amiodarone, Bretylium tosilate, Bunaftine, Dofetilide, Ibutilide
class IV:	Verapamil, Diltiazem see Calcium channel blockers (C08)
class V:	Adenosine, Atropine, Digoxin