Hsien Wu
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Hsien Wu (24 November 1893 - 8 August 1959) was an early protein scientist who was the first to propose that protein denaturation was a purely conformational change, i.e., corresponded to protein unfolding and not to some chemical alteration of the protein.[1] This crucial idea was popularized later by Linus Pauling and Alfred Mirsky.[2]
Wu's son, Ray J. Wu, became a well-respected professor at Cornell University, the Liberty Hyde Bailey Professor of Molecular Genetics and Biology, and has been active in studying transgenic plants, particularly rice.
[edit] References
- ^ Wu, H (1931). "Studies on Denaturation of Proteins. XIII. A Theory of Denaturation". Chinese Journal of Physiology 5: 321–344. Prelimary reports were presented before the XIIIth International Congress of Physiology at Boston (19-24 August 1929) and in the October 1929 issue of the American Journal of Physiology.
- ^ Mirsky, AE, Pauling L (1936). "On the Structure of Native, Denatured, and Coagulated Proteins". Proceedings of the National Academy of Science USA 22: 439–447.
[edit] Further reading
- Edsall, JT (1995). "Hsien Wu and the First Theory of Protein Denaturation". Advances in Protein Chemistry 46: 1–5.
- Wu, DY (1959). Hsien Wu 1893-1959: In Loving Memory. Boston: published privately.
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