Hormone response element

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A hormone response element (HRE) is a short sequence of DNA within the promoter of a gene that is able to bind a specific hormone receptor complex and therefore regulate transcription[1]. The sequence is most commonly a pair of inverted repeats separated by three nucleotides, which also indicates that the receptor binds as a dimer. A gene may have many different response elements, allowing complex control to be exerted over the level and rate of transcription.[2]

[edit] References

  1. ^ Steroid Hormone Receptors and their Response Elements. Retrieved on 2006-11-09.
  2. ^ Lodish, et al. (2004). Molecular Cell Biology, 5th edn, W.H. Freeman and Company. 0-7167-4366-3.
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