Homatropine

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Image:Homatropine.png
Homatropine
Systematic (IUPAC) name
(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl) 2-hydroxy-2-phenyl-acetate bromide
Identifiers
CAS number	80-49-9
ATC code	A02BX03
PubChem	6646
DrugBank	APRD01017
Chemical data
Formula	C17H24BrNO3
Mol. weight	370.28 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Homatropine (Equipin®, Isopto Homatropine®) is an anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic, to temporarily paralyze accommodation, and as a mydriatic, to dilate the pupil.

Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide or methylbromide salt

[edit] Side effects

• Blurred vision
• Sensitivity to light

[edit] Contraindications

• Untreated glaucoma
• Myasthenia gravis
• Severe heart failure
• Thyrotoxicosis