Herpes B Virus
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B Virus(Cercopithecine herpesvirus 1, herpesvirus simiae, Herpes B virus) is the endemic simplexvirus of macaques, in which the virus exhibits pathogenesis similar to that of herpes simplex virus in humans. Conversely, when humans are zoonotically infected with B virus, undiagnosed and untreated patients can present with severe CNS disease, resulting in permanent neurological disfunction or death. It is estimated that the mortality rate for untreated patients is near 80%. The last known fatality occurred when a worker at the Yerkes National Primate Research Center was infected in 1997. Proper personal protective equipment is essential when working with macaque monkeys, especially those who have tested positive for the virus. Bites and scratches must be cleansed immediately and samples from the macaque and human should be sent for B virus diagnostic testing as recommended by the B Virus Working Group here: BVIRUS.pdf
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