Good Laboratory Practice

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Good Laboratory Practice generally refers to a system of management controls for laboratories and research organisations to ensure the consistency and reliability of results as outlined in the OECD Principles of GLP and national regulations.

GLP applies to non-clinical studies conducted for the assessment of the safety of chemicals to man, animals and the environment. The internationally accepted definition is as follows:

GLP is a quality system and the manner in which non-clinical safety studies are: Planned, performed, monitored, recorded, reported and archived.

[edit] Safe laboratory practice

It is important to be safe when working in a laboratory. Wear personal protective equipment (PPE) such as goggles, gloves or respiratory protection and be safe.

Avoid exposure to hazardous material by planning all procedures before starting any laboratory work.

The production of aerosols due to poor technique (squirting the last drop out of pipettes) and the spread of contamination due to spills is completely avoidable and especially important if you are handling infectious material, radiochemicals, carcinogens or highly toxic material.

Keep stocks of reagents and solvents in the laboratory to a minimum, this reduces the risk of wastage due to contamination, it reduces the potential fire load and reduces the potential for harm.