Glucose isomerase

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Glucose phosphate isomerase
Enzyme Phosphoglucose isomerase PDB Code PDB 1GZV Organism Pig Tissue Muscle Complexed molecules 5-phosphoarabinoate
Symbol(s):	GPI
Genetic data
Locus:	Chr. 19 q13.1
Database Links
EC number:	5.3.1.9
Entrez:	2821
OMIM:	172400
RefSeq:	NM_000175
UniProt:	P06744

Glucose isomerase is an enzyme (EC 5.3.1.9) that catalyzes the conversion of glucose into fructose. In the glycolysis pathway phosphoglucose isomerase converts glucose-6-phosphate to fructose-6-phosphate. These reactions are reversible.

Contents 1 In glycolysis 2 As a glucose isomerase 3 Other functions 4 See also

[edit] In glycolysis

α-D-Glucose 6-phosphate	Phosphoglucose isomerase		β-D-Fructose 6-phosphate
	Phosphoglucose isomerase

Compound C00668 at KEGG Pathway Database. Enzyme 5.3.1.9 at KEGG Pathway Database. Compound C05345 at KEGG Pathway Database. Reaction R00771 at KEGG Pathway Database.

[edit] As a glucose isomerase

D-Glucose	Phosphoglucose isomerase		D-Fructose
			Image:D-fructose wpmp.png
	Phosphoglucose isomerase

[edit] Other functions

There is evidence that phosphoglucose isomerase acts as a molecular messenger. It is produced and secreted by white blood cells, and acts to regulate the growth of several different cell types.

[edit] See also