Genetic architecture
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Genetic architecture refers to the underlying genetic basis of a phenotypic trait. It encompasses both the number of genes and their importance in determining the phenotype (e.g., many genes of small effect vs. few genes of large effect).
| The development of phenotype | |
|---|---|
| Key concepts | Genotype-phenotype distinction · Norms of reaction · Gene-environment interaction · Heritability · Quantitative genetics |
| Genetic architecture | Dominance relationship · Epistasis · Polygenic inheritance · Pleiotropy · Plasticity · Canalisation · Fitness landscape |
| Non-genetic influences | Epigenetic inheritance · Epigenetics · Maternal effect · Dual inheritance theory |
| Developmental architecture | Segmentation · Modularity |
| Evolution of genetic systems | Evolvability · Mutational robustness · Evolution of sex |
| Influential figures | C. H. Waddington · Richard Lewontin |
| Debates | Nature versus nurture |
| List of evolutionary biology topics | |
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