Fumarate

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A fumarate is a salt or ester of the organic compound fumaric acid, a dicarboxylic acid.

[edit] Biochemistry

A precursor to L-malate in the Krebs tricarboxylic acid cycle. It is formed by the oxidation of adenylsuccinate by succinate dehydrogenase.

Fumarate is converted by fumarase to malate.

In simple fumarate is used by cells to produce Energy (ATP) from food.

[edit] See also


 v  d  e 
Citric Acid Cycle Metabolic Pathway
Oxaloacetate Malate Fumarate Succinate Succinyl CoA
Acetyl CoA NADH + H+ NAD+ H2O FADH2 FAD CoA + ATP Pi + ADP
+ H2O NADH + H+ + CO2
CoA NAD+
H2O H2O NADP+ NADPH + H+ CO2
Citrate cis-Aconitate Isocitrate Oxalosuccinate Alpha-ketoglutarate


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