Flupentixol

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Flupentixol chemical structure
Flupentixol
Systematic (IUPAC) name
2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene] propyl]piperazin-1-yl]ethanol
Identifiers
CAS number 2709-56-0
ATC code N05AF01
PubChem 17012
DrugBank APRD00388
Chemical data
Formula C23H25F3N2OS
Mol. weight 434.519 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 19 to 39 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Prescription only

Routes Oral

Flupenthixol is a synthetic compound that acts on a subset of dopamine receptors. It specifically antagonizes D1 and D2 dopamine receptors (as well as serotonin). Flupenthixol decanoate ester is used as an intramuscular depot injection as a long-acting antipsychotic, lasting up to 4 weeks from a single injection.


Antipsychotics (N05A) edit
Phenothiazine typical antipsychotics:

Chlorpromazine, Fluphenazine, Mesoridazine, Perphenazine, Prochlorperazine, Promazine, Thioridazine, Trifluoperazine

Other typical antipsychotics:

Chlorprothixene, Droperidol, Flupentixol, Haloperidol, Loxapine, Molindone, Pimozide, Sulforidazine, Thiothixene

Atypical antipsychotics:

Abilify, Amisulpride, Aripiprazole, Clozapine, Olanzapine, Quetiapine, Risperidone/Paliperidone, Sertindole, Sulpiride, Ziprasidone, Zotepine


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