Fibrosing Mediastinitis
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Fibrosing Mediastinitis is a rare benign disorder caused by rapid and repeated growth of acellular collagen and fibrous tissue within the chest including the central vessels and airways. (1) Patients of fibrosing mediastinitis are usually young and can present with symptoms such as obstruction or compression of the central airways, esophagus, pulmonary veins or arteries and superior vena cava (SVC). Fibrosing Mediastinitis can be either idiopathic (arising spontaneously) or from an abnormal immunologic response to Histoplasma capsulatum (histoplasmosis). (2)
(1) Rossi, McAdams, Rosado-de-Chrstenson, Franks, and Jeffrey Galvin. (2001). From the Archives of the AFIP: Fibrosing Mediastinitis. RadioGraphics May - June, volume 21. 737-755.
(2) Kauffman, C. 2003. Clinical Mycology. Chapter 18: Histoplasmosis. 285- 298. Oxford University Press, Inc.
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