Fibromuscular dysplasia
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Fibromuscular dysplasia is a disease that can causes renal artery stenosis, carotid artery stenosis and in fewer cases stenosis in the abdomen artheries , which can leads to hypertension, strokes and others problems.
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[edit] Etiology
Fibromuscular dysplasia tends to occur in females between 14 and 50 years of age.
[edit] Pathology
Fibromuscular dysplasia is characterized by fibrous thickening of the intima, media, or adventitia of the renal artery. The lesions cause narrowing of the artery lumen.
[edit] Hypertension
As a result of renal artery stenosis, the kidney's afferent arteriolar pressure falls. The renin-angiotensin system is activated, causing fluid retention and hypertension.
[edit] Symptoms
One of the symptoms can be a continuous headache. If this disease is not treated, usually the person will have a major stroke and die. In other cases, the person might have seizures.
[edit] Treatment
ACE inhibitors, and Angiotensin II receptor antagonists are often initial treatments of fibromuscular dysplasia. Refractory cases are often treated by stenting the renal artery. <http://www.cardiosource.com/ExpertOpinions/hottopics/article.asp?paperID=82/>
[edit] External links
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