Ferrochelatase
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ferrochelatase
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| Identifiers | |
| Symbol(s) | FECH |
| Entrez | 2235 |
| OMIM | 177000 |
| RefSeq | NM_000140 |
| UniProt | P22830 |
| Other data | |
| EC number | 4.99.1.1 |
| Locus | Chr. 18 q21.2-21.3 |
Ferrochelatase is an enzyme involved in the eighth step of porphyrin metabolism, converting protoporphyrin IX into heme. It catalyses reaction: protoporphyrin + Fe(2+) = protoheme + 2 H(+). A ferrochelatase enzyme consists of 497 amino acid residues with a m.w. of 55.4 kDa.
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Orientation of Ferrochelatase in membrane
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