Fenoldopam


Fenoldopam
Systematic (IUPAC) name
8-chloro-2-(4-hydroxyphenyl)- 4-azabicyclo[5.4.0] undeca-7,9,11-triene-9,10-diol
Identifiers
CAS number	67227-57-0
ATC code	C01 CA19
PubChem	3341
DrugBank	APRD00969
Chemical data
Formula	C₁₆H₁₆N Cl O₃
Mol. weight	305.756 g/mol
Pharmacokinetic data
Bioavailability	n/a
Metabolism	Hepatic (CYP not involved)
Half life	5 minutes
Excretion	Renal (90%) and fecal (10%)
Therapeutic considerations
Licence data	US
Pregnancy cat.	B(US)
Legal status
Routes	Intravenous

Fenoldopam is a synthetic compound that acts as a dopamine D₁ receptor agonist. Fenoldopam is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation, decreasing afterload and also through specific dopamine receptors along the nephron promoting sodium excretion.

Dopamine agonists (N04BC) edit
Apomorphine, Bromocriptine, Cabergoline, Dihydrexidine, Dihydroergocryptine mesylate, Fenoldopam, Lisuride hydrogen maleate, Pergolide, Piribedil, Pramipexole, Quinpirole, Ropinirole, Rotigotine, SKF 38393, SKF 82958

Adrenergic and dopaminergic agents (C01CA)edit
	Dobutamine, Dopamine, Epinephrine, Fenoldopam, Isoprenaline, Metaraminol, Midodrine, Norepinephrine, Octopamine, Phenylephrine

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