Extraglomerular mesangial cells

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Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the distal convoluted tubule and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood.^[1]

[edit] See also

• mesangium
• intraglomerular mesangial cells

[edit] External links

• UIUC Histology Subject 1010
• Dorlands/Elsevier m_10/12526143

[edit] References

1. ^ Junqueira, Luiz C., Jose Carneiro (2003). Basic Histology. McGraw-Hill. ISBN 0-07-141365.

Urinary system - Kidney - edit
Renal fascia | Renal capsule | Renal cortex  (Renal column) | Renal medulla (Renal sinus, Renal pyramids) | Renal lobe | Cortical lobule | Medullary ray | Nephron
afferent circulation: Renal artery → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Renal corpuscle (Glomerulus, Bowman's capsule) kidney tubule: Proximal tubule → Loop of Henle (Descending, Thin ascending, Thick ascending)  → Distal convoluted tubule → Connecting tubule → Collecting ducts → Duct of Bellini → Renal papilla → Minor calyx → Major calyx → Renal pelvis → Ureter efferent circulation: Glomerulus → Efferent arterioles → Peritubular capillaries/Vasa recta → Arcuate vein→ Interlobar veins→ Renal vein juxtaglomerular apparatus: Macula densa, Juxtaglomerular cells, Extraglomerular mesangial cells
Renal physiology
Filtration - Ultrafiltration | Countercurrent exchange | Glomerular basement membrane | Podocyte | Filtration slits | Intraglomerular mesangial cells Hormones affecting filtration - Antidiuretic hormone (ADH) | Aldosterone | Atrial natriuretic peptide Endocrine - Renin | Erythropoietin (EPO) | Calcitriol (Active vitamin D) | Prostaglandins
Assessing Renal function / Measures of dialysis
Glomerular filtration rate | Creatinine clearance | Renal clearance ratio | Urea reduction ratio | Kt/V | Standardized Kt/V | Hemodialysis product