Epidural space

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Epidural space
The medulla spinalis and its membranes.
Diagrammatic representation of a section across the top of the skull, showing the membranes of the brain, etc.
Latin spatium extradurale
Gray's subject #193 875
Dorlands/Elsevier s_16/12746475
For a discussion about the anesthetic procedure, see Epidural.

In the spine, the epidural space is the space outside the tough membrane called the dura mater (sometimes called the "dura"), and within the spinal canal, which is formed by the surrounding vertebrae. Adherent to the inside of the dura is a much thinner and more fragile membrane, the arachnoid mater. Enclosed within the arachnoid is the subarachnoid space, which contains the cerebrospinal fluid, and the spinal cord.

[edit] In humans

In the spine, the epidural space contains lymphatics, spinal nerve roots, loose fatty tissue, small arteries, and a network of large, thin-walled blood vessels called the epidural venous plexus.

The upper limit of the epidural space is the foramen magnum, which is the point where the spine meets the base of the skull. The lower limit is at the tip of the sacrum, at the sacrococcygeal membrane.

In the head, the dura is continuous with the periosteum, the tough fibrous lining of the inside of the skull. This means that, in the head, the epidural space is known as a potential space, which means that normally it does not exist. In rare circumstances, a torn artery (e.g. the middle meningeal artery) may cause bleeding which is sufficient to separate both the dura and periosteum from the bone; this is an epidural hematoma.

The space between the dura and the arachnoid (in both head and spine), the subdural space, is also a potential space. Bleeding may also occur here.

[edit] In other mammals

In other mammals, the relationship between the spinal canal and its contents is similar to that in humans, although many species possess a tail into which the epidural space is prolonged.

A unique property of the epidural venous plexus is that the veins are prevented from collapsing due to external pressure because the bony spinal canal prevents that pressure being transmitted. This means that for many diving mammals, e.g. whales, when diving a large fraction of venous return to the heart takes place via the epidural space, as veins such as the vena cava may be substantially compressed by the pressure at depth.

[edit] External links

Spinal cord

epidural space, dura mater, subdural space, arachnoid mater, subarachnoid space, pia mater, denticulate ligaments, conus medullaris, cauda equina, filum terminale, cervical enlargement, lumbar enlargement, anterior median fissure, dorsal root, dorsal root ganglion, dorsal ramus, ventral root, ventral ramus, sympathetic trunk, gray ramus communicans, white ramus communicans

grey matter: central canal, substantia gelatinosa of Rolando, reticular formation, substantia gelatinosa centralis, interneuron, anterior horn, lateral horn, posterior horn (column of Clarke, dorsal spinocerebellar tract)

white matter: anterior funiculus: descending (anterior corticospinal tract, vestibulospinal fasciculus, tectospinal tract), ascending (anterior spinothalamic tract, anterior proper fasciculus)

lateral funiculus: descending (lateral corticospinal tract, rubrospinal tract, olivospinal tract), ascending dorsal spinocerebellar tract, ventral spinocerebellar tract, spinothalamic tract, lateral spinothalamic tract, anterior spinothalamic tract, spinotectal tract, posterolateral tract, lateral proper fasciculus, medial longitudinal fasciculus

posterior funiculus: fasciculus gracilis, fasciculus cuneatus, posterior proper fasciculus

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