ICD-10 Chapter IV: Endocrine, nutritional and metabolic diseases

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Contents 1 E00-E35 - Endocrine diseases 1.1 (E00-E07) Thyroid gland / Thyroid hormone 1.2 (E10-E16) Pancreas / Insulin, glucagon 1.2.1 (E10-E14) Diabetes mellitus 1.2.2 (E15-E16) Other disorders of glucose regulation and pancreatic internal secretion 1.3 (E20-E21) Parathyroid gland / PTH 1.4 (E22-E23) Pituitary gland / ADH, oxytocin, GH, ACTH, TSH, LH, FSH, prolactin 1.5 (E24-E27) Adrenal gland / Aldosterone, cortisol, epinephrine, norepinephrine 1.6 (E28-E30) Gonads / Estrogen, androgens, testosterone, etc. 1.7 (E31-E35) Other 2 E40-68 - Nutritional diseases 2.1 (E40-E46) Malnutrition 2.2 (E50-E64) Other nutritional deficiencies 2.3 (E65-E68) Obesity and other hyperalimentation 3 E70-E90 - Metabolic diseases 3.1 (E70-E79) Metabolic disorders of proteins, fats, and carbohydrates 3.1.1 (E70-E72) Amino-acids 3.1.2 (E73-E74) Carbohydrates 3.1.3 (E75) Lipids 3.1.4 (E76-E78) Combinations 3.2 (E79-E90) Other metabolic disorders 4 See also

[edit] E00-E35 - Endocrine diseases

[edit] (E00-E07) Thyroid gland / Thyroid hormone

• (E00.) Congenital iodine-deficiency syndrome

• (E01.) Iodine-deficiency-related thyroid disorders and allied conditions
  • (E01.0) Iodine-deficiency-related diffuse (endemic) goitre
  • (E01.1) Iodine-deficiency-related multinodular (endemic) goitre
  • (E01.2) Iodine-deficiency-related (endemic) goitre, unspecified
  • (E01.8) Other iodine-deficiency-related thyroid disorders and allied condition

• (E02.) Subclinical iodine-deficiency hypothyroidism
• (E03.) Other hypothyroidism
  • (E03.0) Congenital hypothyroidism with diffuse goitre
  • (E03.1) Congenital hypothyroidism without goitre
  • (E03.2) Hypothyroidism due to medicaments and other exogenous substances
  • (E03.3) Postinfectious hypothyroidism
  • (E03.4) Atrophy of thyroid (acquired)
  • (E03.5) Myxoedema coma
• (E04.) Other nontoxic goitre

• (E05.) Thyrotoxicosis (hyperthyroidism)
  • (E05.0) Thyrotoxicosis with diffuse goitre
    • Graves' disease
  • (E05.1) Thyrotoxicosis with toxic single thyroid nodule
  • (E05.2) Thyrotoxicosis with toxic multinodular goitre
  • (E05.3) Thyrotoxicosis from ectopic thyroid tissue
  • (E05.4) Thyrotoxicosis factitia
  • (E05.5) Thyroid crisis or storm
  • (E05.8) Other thyrotoxicosis
  • (E05.9) Thyrotoxicosis, unspecified

• (E06.) Thyroiditis
  • (E06.0) Acute thyroiditis
  • (E06.1) Subacute thyroiditis
  • (E06.2) Chronic thyroiditis with transient thyrotoxicosis
  • (E06.3) Autoimmune thyroiditis
    • Hashimoto's thyroiditis
  • (E06.4) Drug-induced thyroiditis
  • (E06.5) Other chronic thyroiditis
  • (E06.9) Thyroiditis, unspecified

• (E07.) Other disorders of thyroid

[edit] (E10-E16) Pancreas / Insulin, glucagon

[edit] (E10-E14) Diabetes mellitus

• Note: the following conditions are subtypes of each code from E10-14:
  • (E1x.0) Diabetic coma
  • (E1x.1) Diabetic ketoacidosis
  • (E1x.2) Diabetic nephropathy
  • (E1x.3) Diabetic retinopathy
  • (E1x.4) Diabetic neuropathy
  • (E1x.5) Diabetic angiopathy
  • (E1x.6) Diabetic arthropathy
• (E10.) Insulin-dependent diabetes mellitus
• (E11.) Non-insulin-dependent diabetes mellitus
• (E12.) Malnutrition-related diabetes mellitus
• (E13.) Other specified diabetes mellitus
• (E14.) Unspecified diabetes mellitus

[edit] (E15-E16) Other disorders of glucose regulation and pancreatic internal secretion

• (E15.) Nondiabetic hypoglycaemic coma
• (E16.) Other disorders of pancreatic internal secretion
  • (E16.0) Drug-induced hypoglycaemia without coma
  • (E16.1) Other hypoglycaemia
  • (E16.2) Hypoglycaemia, unspecified
  • (E16.3) Increased secretion of glucagon
  • (E16.4) Abnormal secretion of gastrin
    • Hypergastrinaemia
    • Zollinger-Ellison syndrome
  • (E16.8) Other specified disorders of pancreatic internal secretion
  • (E16.9) Disorder of pancreatic internal secretion, unspecified

[edit] (E20-E21) Parathyroid gland / PTH

• (E20.) Hypoparathyroidism
  • (E20.0) Idiopathic hypoparathyroidism
  • (E20.1) Pseudohypoparathyroidism

• (E21.) Hyperparathyroidism and other disorders of parathyroid gland
  • (E21.0) Primary hyperparathyroidism
  • (E21.1) Secondary hyperparathyroidism, not elsewhere classified

[edit] (E22-E23) Pituitary gland / ADH, oxytocin, GH, ACTH, TSH, LH, FSH, prolactin

• (E22.) Hyperfunction of pituitary gland
  • (E22.0) Acromegaly and pituitary gigantism
  • (E22.1) Hyperprolactinaemia
  • (E22.2) Syndrome of inappropriate secretion of antidiuretic hormone
    • Central precocious puberty

• (E23.) Hypofunction and other disorders of pituitary gland
  • (E23.0) Hypopituitarism
    • Sheehan's syndrome
    • Hypogonadotropic hypogonadism
    • Kallmann syndrome
  • (E23.1) Drug-induced hypopituitarism
  • (E23.2) Diabetes insipidus
  • (E23.3) Hypothalamic dysfunction, not elsewhere classified

[edit] (E24-E27) Adrenal gland / Aldosterone, cortisol, epinephrine, norepinephrine

• (E24.) Cushing's syndrome

• (E25.) Adrenogenital disorders
  • (E25.0) Congenital adrenogenital disorders associated with enzyme deficiency
    • Congenital adrenal hyperplasia
      • Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

• (E26.) Hyperaldosteronism
  • (E26.0) Primary hyperaldosteronism
    • Conn's syndrome
    • Primary aldosteronism due to adrenal hyperplasia (bilateral)
  • (E26.1) Secondary hyperaldosteronism
  • (E26.8) Other hyperaldosteronism
    • Bartter's syndrome
  • (E26.9) Hyperaldosteronism, unspecified

• (E27.) Other disorders of adrenal gland
  • (E27.0) Other adrenocortical overactivity
  • (E27.1) Primary adrenocortical insufficiency
    • Addison's disease
  • (E27.2) Addisonian crisis
  • (E27.3) Drug-induced adrenocortical insufficiency
  • (E27.4) Other and unspecified adrenocortical insufficiency
    • Hypoaldosteronism
    • Adrenocortical insufficiency NOS
  • (E27.5) Adrenomedullary hyperfunction

[edit] (E28-E30) Gonads / Estrogen, androgens, testosterone, etc.

• (E28.) Ovarian dysfunction
  • (E28.0) Estrogen excess
  • (E28.1) Androgen excess
  • (E28.2) Polycystic ovarian syndrome
  • (E28.3) Primary ovarian failure
    • Premature menopause NOS

• (E29.) Testicular dysfunction
  • (E29.0) Testicular hyperfunction
  • (E29.1) Testicular hypofunction
    • 5-Alpha-reductase deficiency (with male pseudohermaphroditism)
    • Testicular hypogonadism NOS

• (E30.) Disorders of puberty, not elsewhere classified
  • (E30.0) Delayed puberty
  • (E30.1) Precocious puberty
  • (E30.8) Other disorders of puberty
    • Premature thelarche

[edit] (E31-E35) Other

• (E31.) Polyglandular dysfunction
  • (E31.0) Autoimmune polyglandular failure
    • Schmidt's syndrome
  • (E31.1) Polyglandular hyperfunction

• (E32.) Diseases of thymus
  • (E32.0) Persistent hyperplasia of thymus
  • (E32.1) Abscess of thymus

• (E34.) Other endocrine disorders
  • (E34.0) Carcinoid syndrome
  • (E34.1) Other hypersecretion of intestinal hormones
  • (E34.2) Ectopic hormone secretion, not elsewhere classified
  • (E34.3) Short stature, not elsewhere classified
  • (E34.4) Constitutional tall stature
  • (E34.5) Androgen resistance syndrome
    • Reifenstein's syndrome
  • (E34.8) Other specified endocrine disorders
    • Progeria

• (E35.) Disorders of endocrine glands in diseases classified elsewhere
  • (E35.0) Disorders of thyroid gland in diseases classified elsewhere
  • (E35.1) Disorders of adrenal glands in diseases classified elsewhere
  • (E35.8) Disorders of other endocrine glands in diseases classified elsewhere

[edit] E40-68 - Nutritional diseases

[edit] (E40-E46) Malnutrition

• (E40.) Kwashiorkor
• (E41.) Nutritional marasmus
• (E42.) Marasmic kwashiorkor
• (E43.) Unspecified severe protein-energy malnutrition
• (E44.) Protein-energy malnutrition of moderate and mild degree
• (E45.) Retarded development following protein-energy malnutrition
• (E46.) Unspecified protein-energy malnutrition

[edit] (E50-E64) Other nutritional deficiencies

• (E50.) Vitamin A deficiency
  • (E50.0) Vitamin A deficiency with conjunctival xerosis
  • (E50.1) Vitamin A deficiency with Bitot's spot and conjunctival xerosis
  • (E50.2) Vitamin A deficiency with corneal xerosis
  • (E50.3) Vitamin A deficiency with corneal ulceration and xerosis
  • (E50.4) Vitamin A deficiency with keratomalacia
  • (E50.5) Vitamin A deficiency with night blindness
  • (E50.6) Vitamin A deficiency with xerophthalmic scars of cornea
  • (E50.7) Other ocular manifestations of vitamin A deficiency
    • Xerophthalmia NOS
• (E51.) Thiamine deficiency
  • (E51.1) Beriberi
  • (E51.2) Wernicke's encephalopathy
• (E52.) Niacin deficiency (pellagra)
• (E53.) Deficiency of other B group vitamins
  • (E53.0) Riboflavin deficiency
    • Ariboflavinosis
  • (E53.1) Pyridoxine deficiency
  • (E53.8) Deficiency of other specified B group vitamins
• (E54.) Ascorbic acid deficiency
  • Scurvy
• (E55.) Vitamin D deficiency
  • (E55.0) Rickets, active
• (E56.) Other vitamin deficiencies
  • (E56.0) Deficiency of vitamin E
  • (E56.1) Deficiency of vitamin K
• (E58.) Dietary calcium deficiency
• (E59.) Dietary selenium deficiency
• (E60.) Dietary zinc deficiency
• (E61.) Deficiency of other nutrient elements
  • (E61.1) Iron deficiency
  • (E61.2) Magnesium deficiency
  • (E61.3) Manganese deficiency
  • (E61.4) Chromium deficiency
  • (E61.5) Molybdenum deficiency
  • (E61.6) Vanadium deficiency
• (E63.) Other nutritional deficiencies
  • (E63.0) Essential fatty acid (EFA) deficiency
• (E64.) Sequelae of malnutrition and other nutritional deficiencies

[edit] (E65-E68) Obesity and other hyperalimentation

• (E65.) Localized adiposity
• (E66.) Obesity
• (E67.) Other hyperalimentation
  • (E67.0) Hypervitaminosis A
  • (E67.3) Hypervitaminosis D
• (E68.) Sequelae of hyperalimentation

[edit] E70-E90 - Metabolic diseases

[edit] (E70-E79) Metabolic disorders of proteins, fats, and carbohydrates

[edit] (E70-E72) Amino-acids

• (E70.) Disorders of aromatic amino-acid metabolism
  • (E70.0) Classical phenylketonuria
  • (E70.1) Other hyperphenylalaninaemias
  • (E70.2) Disorders of tyrosine metabolism
    • Alkaptonuria (ILDS E70.210)
    • Ochronosis (ILDS E70.230)
    • Tyrosinaemia
  • (E70.3) Albinism

• (E71.) Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
  • (E71.0) Maple-syrup-urine disease
  • (E71.1) Other disorders of branched-chain amino-acid metabolism
    • Propionic acidemia
    • Methylmalonic acidemia
    • Isovaleric acidemia
  • (E71.2) Disorder of branched-chain amino-acid metabolism, unspecified
  • (E71.3) Disorders of fatty-acid metabolism
    • Muscle carnitine palmityltransferase deficiency

• (E72.) Other disorders of amino-acid metabolism
  • (E72.0) Disorders of amino-acid transport
    • Cystinuria
    • Cystinosis
    • Hartnup disease
  • (E72.1) Disorders of sulfur-bearing amino-acid metabolism
    • Homocystinuria
  • (E72.2) Disorders of urea cycle metabolism
    • Citrullinaemia
    • Hyperammonemia
  • (E72.3) Disorders of lysine and hydroxylysine metabolism
    • Glutaric aciduria
  • (E72.4) Disorders of ornithine metabolism
  • (E72.5) Disorders of glycine metabolism

[edit] (E73-E74) Carbohydrates

• (E73.) Lactose intolerance

• (E74.) Other disorders of carbohydrate metabolism
  • (E74.0) Glycogen storage disease
    • Glycogen storage disease type I (von Gierke's disease)
    • Glycogen storage disease type II (Pompe's disease)
    • Glycogen storage disease type III
    • Glycogen storage disease type IV
    • Glycogen storage disease type V (McArdle's disease)
  • (E74.1) Disorders of fructose metabolism
    • Hereditary fructose intolerance
  • (E74.2) Disorders of galactose metabolism
    • Galactosaemia

[edit] (E75) Lipids

• (E75.) Disorders of sphingolipid metabolism and other lipid storage disorders
  • (E75.0) GM 2 gangliosidosis
    • Sandhoff disease
    • Tay-Sachs disease
  • (E75.1) Other gangliosidosis
    • GM 1
    • GM 3
    • Mucolipidosis IV
  • (E75.2) Other sphingolipidosis
    • Gaucher's disease (ILDS E75.220)
    • Niemann-Pick disease (ILDS E75.230)
    • Farber's disease (ILDS E75.240)
    • Fabry's disease (ILDS E75.250)
  • (E75.3) Sphingolipidosis, unspecified
  • (E75.4) Neuronal ceroid lipofuscinosis
    • Batten disease (Type 3)
    • Bielschowsky-Jansky disease (Type 2)
    • Kufs disease (Type 4)
    • Spielmeyer-Vogt disease (Type 3)
  • (E75.5) Other lipid storage disorders
    • Cerebrotendinous cholesterosis (van Bogaert-Scherer-Epstein)
    • Wolman's disease
  • (E75.6) Lipid storage disorder, unspecified

[edit] (E76-E78) Combinations

• (E76.) Disorders of glycosaminoglycan metabolism
  • (E76.0) Mucopolysaccharidosis, type I
    • Hurler syndrome
  • (E76.1) Mucopolysaccharidosis, type II
    • Hunter syndrome
  • (E76.2) Other mucopolysaccharidoses
    • Sanfilippo syndrome
    • Morquio syndrome

• (E77.) Disorders of glycoprotein metabolism
  • (E77.0) Defects in post-translational modification of lysosomal enzymes
    • Mucolipidosis II (I-cell disease)
    • Mucolipidosis III (pseudo-Hurler polydystrophy)
  • (E77.1) Defects in glycoprotein degradation
    • Aspartylglucosaminuria
    • Fucosidosis
    • Mannosidosis
    • Sialidosis (mucolipidosis I)

• (E78.) Disorders of lipoprotein metabolism and other lipidaemias
  • (E78.0) Pure hypercholesterolaemia
    • Familial hypercholesterolaemia
    • Fredrickson's hyperlipoproteinaemia, type IIa
    • Hyperbetalipoproteinaemia
    • Hyperlipidaemia, group A
    • Low-density-lipoprotein-type (LDL) hyperlipoproteinaemia
  • (E78.1) Pure hyperglyceridaemia
    • Endogenous hyperglyceridaemia
    • Fredrickson's hyperlipoproteinaemia, type IV
    • Hyperlipidaemia, group B
    • Hyperprebetalipoproteinaemia
    • Very-low-density-lipoprotein-type (VLDL) hyperlipoproteinaemia
  • (E78.2) Mixed hyperlipidaemia
    • Broad- or floating-betalipoproteinaemia
    • Fredrickson's hyperlipoproteinaemia, type IIb or III
    • Hyperbetalipoproteinaemia with prebetalipoproteinaemia
    • Hypercholesterolaemia with endogenous hyperglyceridaemia
    • Hyperlipidaemia, group C
    • Tubero-eruptive xanthoma
    • Xanthoma tuberosum
  • (E78.3) Hyperchylomicronaemia
    • Fredrickson's hyperlipoproteinaemia, type I or V
    • Hyperlipidaemia, group D
    • Mixed hyperglyceridaemia
  • (E78.4) Other hyperlipidaemia
    • Familial combined hyperlipidaemia
  • (E78.5) Hyperlipidaemia, unspecified
  • (E78.6) Lipoprotein deficiency
    • Abetalipoproteinaemia
    • High-density lipoprotein deficiency
    • Hypoalphalipoproteinaemia
    • Hypobetalipoproteinaemia (familial)
    • Lecithin cholesterol acyltransferase deficiency
    • Tangier disease

[edit] (E79-E90) Other metabolic disorders

• (E79.) Disorders of purine and pyrimidine metabolism
  • (E79.0) Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
  • (E79.1) Lesch-Nyhan syndrome
  • (E79.8) Other disorders of purine and pyrimidine metabolism
    • Hereditary xanthinuria

• (E80.) Disorders of porphyrin and bilirubin metabolism
  • (E80.0) Hereditary erythropoietic porphyria
    • Erythropoietic protoporphyria (ILDS E80.010)
    • Erythropoietic porphyria, congenital (ILDS E80.020)
    • Gunther's disease (ILDS (ILDS E80.020)
    • Erythropoietic porphyria (ILDS (ILDS E80.030)
    • Erythropoietic coproporphyria (ILDS E80.040)
  • (E80.1) Porphyria cutanea tarda
    • Sporadic porphyria cutanea tarda (ILDS E80.110)
    • Familial porphyria cutanea tarda (ILDS E80.120)
  • (E80.2) Other porphyria
    • Acute intermittent porphyria (ILDS E80.210)
    • Hereditary coproporphyria (ILDS E80.222)
    • Variegate porphyria (ILDS E80.230)
    • Chester porphyria (ILDS E80.232)
    • Porphyria, hepatic (ILDS E80.240)
    • Pseudoporphyria (ILDS E80.250)
    • Toxic porphyria (ILDS E80.260)
    • Hepatoerythropoietic porphyria (ILDS E80.282)
    • Porphyria, NOS (ILDS E80.290)
  • (E80.3) Defects of catalase and peroxidase
    • Acatalasia (Takahara)
  • (E80.4) Gilbert's syndrome
  • (E80.5) Crigler-Najjar syndrome
  • (E80.6) Other disorders of bilirubin metabolism
    • Dubin-Johnson syndrome
    • Rotor's syndrome
  • (E80.7) Disorder of bilirubin metabolism, unspecified

• (E83.) Disorders of mineral metabolism
  • (E83.0) Disorders of copper metabolism
    • Wilson's disease
    • Menkes disease
  • (E83.1) Disorders of iron metabolism
    • Hemochromatosis
  • (E83.2) Disorders of zinc metabolism
    • Acrodermatitis enteropathica
  • (E83.3) Disorders of phosphorus metabolism
    • Acid phosphatase deficiency
    • Familial hypophosphataemia
    • Hypophosphatasia
    • Vitamin-D-resistant osteomalacia
    • Vitamin-D-resistant rickets
  • (E83.4) Disorders of magnesium metabolism
    • Hypermagnesemia
    • Hypomagnesemia
  • (E83.5) Disorders of calcium metabolism
    • Familial hypocalciuric hypercalcaemia
    • Idiopathic hypercalciuria

• (E84.) Cystic fibrosis

• (E85.) Amyloidosis
  • (E85.0) Non-neuropathic heredofamilial amyloidosis
    • Familial Mediterranean fever

• (E86.) Volume depletion
  • Dehydration
  • Hypovolaemia

• (E87.) Other disorders of fluid, electrolyte and acid-base balance
  • (E87.0) Hyperosmolality and hypernatraemia
  • (E87.1) Hypo-osmolality and hyponatraemia
  • (E87.2) Acidosis
    • Respiratory acidosis
    • Metabolic acidosis
    • Lactic acidosis
  • (E87.3) Alkalosis
  • (E87.4) Mixed disorder of acid-base balance
  • (E87.5) Hyperkalaemia
  • (E87.6) Hypokalaemia
  • (E87.7) Fluid overload
  • (E87.8) Other disorders of electrolyte and fluid balance, not elsewhere classified
    • Electrolyte imbalance NOS
    • Hyperchloraemia
    • Hypochloraemia

• (E88.) Other metabolic disorders
  • (E88.0) Disorders of plasma-protein metabolism, not elsewhere classified
    • Alpha-1-antitrypsin deficiency
  • (E88.1) Lipodystrophy, not elsewhere classified
  • (E88.2) Lipomatosis, not elsewhere classified

• (E89.) Postprocedural endocrine and metabolic disorders, not elsewhere classified
  • (E89.0) Postprocedural hypothyroidism
  • (E89.1) Postprocedural hypoinsulinaemia
  • (E89.2) Postprocedural hypoparathyroidism
  • (E89.3) Postprocedural hypopituitarism
  • (E89.4) Postprocedural ovarian failure
  • (E89.5) Postprocedural testicular hypofunction
  • (E89.6) Postprocedural adrenocortical(-medullary) hypofunction

• (E90.) Nutritional and metabolic disorders in diseases classified elsewhere

[edit] See also

• List of ICD-10 codes
• International Statistical Classification of Diseases and Related Health Problems
• List of ICD-9 codes 240-279: Endocrine, nutritional and metabolic diseases, and immunity disorders