DTPA

From Wikipedia, the free encyclopedia

DTPA

General
Systematic name	(Carboxymethyl)iminobis(ethylenenitrilo)]- tetra-acetic acid
Other names	DTPA, Diethylenetriaminepentaacetic acid, Diethylenetriamine-N,N,N',N',N-pentaacetic acid, N,N-Bis(2-(bis-(carboxymethyl)amino)ethyl)-glycine, Pentetic acid
Molecular formula	C₁₄H₂₃N₃O₁₀
SMILES	?
Molar mass	393.3498 g/mol
Appearance	White crystalline solid
CAS number	[67-43-6]
Properties
Density and phase	? g/cm³, ?
Solubility in water	<0.5g/100ml
Melting point	220°C (493.15 K, 428°F)
Boiling point	decomposes at a higher temp.
Acidity (pK_a)	?
Basicity (pK_b)	?
Chiral rotation [α]_D	?°
Viscosity	? cP at ?°C
Structure
Molecular shape	?
Coordination geometry	?
Crystal structure	?
Dipole moment	? D
Hazards
MSDS	External MSDS
Main hazards	?
NFPA 704
Flash point	Does not burn
R/S statement	R: ? S: ?
RTECS number	MB8205000
Supplementary data page
Structure and properties	n, ε_r, etc.
Thermodynamic data	Phase behaviour Solid, liquid, gas
Spectral data	UV, IR, NMR, MS
Related compounds
Other anions	?
Other cations	?
Related ?	?
Related compounds	EDTA, NTA
Except where noted otherwise, data are given for materials in their standard state (at 25°C, 100 kPa) Infobox disclaimer and references

Diethylene triamine pentaacetic acid (DTPA) is an elongated version of EDTA. It has been used to decontaminate humans who are contaminated with plutonium, americium and other actinides as the compound can chelate these heavy metal ions, render them unabsorbed through the digestive tract and also speeds up the release of these metals in urine. It is normally used as the calcium or zinc salt. It should not be taken by people with kidney disease or bone marrow depression, nor by children younger than 18 years old. If the lungs are contaminated by the inhalation of these radioactive materials, a DTPA spray or mist is used. Otherwise it can also be injected intravenously.