Talk:DNA polymerase

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[edit] DNA Polymerase α

In the article it says that it acts both as the Primase enzyme and the Polymerase. According to pg567, World of the Cell (Becker et al, 2006, Benjamin Cummings) although the Primase and the Pol α are closely asssociated they are separate proteins. I've looked through some other literature but its mostly older stuff so is fairly ambiguous.GiollaUidir 08:18, 20 October 2006 (UTC)

Infact, I've found another source that says they are separate: Figure 4-36, pg136, Molecular Cell Biology, Lodish et al., 2004, W.H. Freeman and Company. I'll edit when I get a chance. (Guess who's in the middle of an essay!? :P)GiollaUidir 09:03, 20 October 2006 (UTC)

[edit] Primer removal

Any idea what actually removes the RNA primer from the DNA strand? Pol I in prokaryotes as far as I can see but I can't find what removes it from eukaryotes.GiollaUidir 08:37, 20 October 2006 (UTC)

Yes, I'm talking to myself. 'tis Proliferating Cell Nuclear Antigen-Replication Factor C-DNA Polymerase δ (PCNA-Rfc-DNA Pol δ-a complex formed to stabilise Pol ’s binding to the template) from: Figure 4-36, pg136, Molecular Cell Biology, Lodish et al., 2004, W.H. Freeman and Company.GiollaUidir 09:47, 20 October 2006 (UTC)