Dirithromycin

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Dirithromycin
Systematic (IUPAC) name
(1S,2R,4R,5R,6S,7S,8R,11R,12R,15R,17S)- 5-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy- 6-methyl-oxan-2-yl]oxy-11-ethyl-4,12-dihydroxy- 7-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy- 4,6-dimethyl-oxan-2-yl]oxy-15-(2-methoxyethoxymethyl)- 2,4,6,8,12,17-hexamethyl-10,14-dioxa-16- azabicyclo[11.3.1]heptadecan-9-one
Identifiers
CAS number	62013-04-1
ATC code	J01FA13
PubChem	5464388
DrugBank	APRD00931
Chemical data
Formula	C42H78N2O14
Mol. weight	835.074 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Dirithromycin is a macrolide glycopeptide antibiotic.

[edit] External links

• Duran D, Aviyente V, Baysal C (2004). "A computational approach to the synthesis of dirithromycin.". J Mol Model (Online) 10 (2): 94-101. PMID 14722740.
• Castaldo R, Celli B, Gomez F, LaVallee N, Souhrada J, Hanrahan J (2003). "A comparison of 5-day courses of dirithromycin and azithromycin in the treatment of acute exacerbations of chronic obstructive pulmonary disease.". Clin Ther 25 (2): 542-57. PMID 12749513.
• Mazzei T, Surrenti C, Novelli A, Biagini M, Fallani S, Cassetta M, Conti S, Surrenti E (1999). "Pharmacokinetics of dirithromycin in patients with mild or moderate cirrhosis.". Antimicrob Agents Chemother 43 (7): 1556-9. PMID 10390202.

Glycopeptides (J01, and others) edit
Macrolides: Azithromycin, Clarithromycin, Dirithromycin, Erythromycin, Roxithromycin Others: Aztreonam, Monobactam, Teicoplanin, Vancomycin