Dipeptidyl peptidase-4
From Wikipedia, the free encyclopedia
 |
|
| Ribbon diagram of human DPP-4. From PDB 1PFQ. |
|
|
dipeptidyl-peptidase 4
|
|
| Identifiers | |
| Symbol(s) | DPP4 CD26, ADCP2 |
| Entrez | 1803 |
| OMIM | 102720 |
| RefSeq | NM_001935 |
| UniProt | P27487 |
| Other data | |
| EC number | 3.4.14.5 |
| Locus | Chr. 2 q23-qter |
Dipeptidyl peptidase-4 is an enzyme associated with glucose metabolism. Specifically, it is responsible for the degradation of incretins.
A new class of oral hypoglycemics called dipeptidyl peptidase-4 inhibitors work by inhibiting the action of this enzyme, thereby prolonging incretin effect in vivo.
 |
This enzyme-related article is a stub. You can help Wikipedia by expanding it. |
