Dicyclomine

From Wikipedia, the free encyclopedia

You have new messages (last change).
Dicyclomine chemical structure
Dicyclomine
Systematic (IUPAC) name
2-diethylaminoethyl1- cyclohexylcyclohexane- 1-carboxylate
Identifiers
CAS number 77-19-0
ATC code  ?
PubChem 3042
DrugBank APRD00113
Chemical data
Formula C19H35NO2
Mol. weight 309.487 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding >99%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Dicyclomine is an anticholinergic that blocks muscarinic receptors. Dicyclomine is known as dicycloverine hydrochloride in the UK.

[edit] Clinical uses

Dicyclomine is used to treat intestinal hypermotility, the symptoms of Irritable Bowel Syndrome (IBS) (also known as spastic colon). It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a certain natural substance in the body. It is a smooth muscle relaxer.

In America, it is sold under the trade names: Bentyl, Byclomine, Dibent, Di-Spaz, Dilomine.

It is sold under the trade names Bentylol (Hoechst Marion Roussel), Formulex (ICN), and Lomine (Riva) in Canada.

[edit] Sources

  • Brenner, G. M. (2000). Pharmacology. Philadelphia, PA: W.B. Saunders Company. ISBN 0-7216-7757-6
  • Canadian Pharmacists Association (2000). Compendium of Pharmaceuticals and Specialties (25th ed.). Toronto, ON: Webcom. ISBN 0-919115-76-4

[edit] Links

http://www.medicinenet.com/dicyclomine/article.htm

http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a684007.html

Retrieved from "http://en.wikipedia.org../../../d/i/c/Dicyclomine.html"