Diauxic shift
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Diauxic shift, also known as Diauxic growth, is the phenomenon in which a microorganism, such as a bacterium or yeast, exhausts its preferred nutrient and switches to use of an alternate energy source. For example, in the case of E. coli bacteria, when provided with a mixture of the sugars glucose and lactose, the bacteria first use up glucose before starting to metabolize lactose. Similarly, in the case of yeast (a fungus), the diauxic shift represents a change in metabolism from glucose fermentation (anaerobic respiration) to aerobic respiration as the glucose is depleted. This shift is accompanied by a change from the usage of glycolysis to gluconeogenesis and the glyoxylate cycle.
[edit] References
- Johnston M, Carlson M. 1992. Regulation of carbon and phosphate utilization. In The Molecular and Cellular Biology of the Yeast Saccharomyces cerevisiae, Jones EW , Pringle JR , Broach JR (eds). Cold Spring Harbor Laboratory Press: New York; 193-281.