Dexmedetomidine

From Wikipedia, the free encyclopedia

Dexmedetomidine chemical structure
Dexmedetomidine
Systematic (IUPAC) name
4-[1-(2,3-dimethylphenyl)ethyl]-3H-imidazole
Identifiers
CAS number 113775-47-6
ATC code N05CM18
PubChem 68602
DrugBank APRD00578
Chemical data
Formula C13H16N2
Mol. weight 200.28 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 94%
Metabolism  ?
Half life 2 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Dexmedetomidine is a sedative medication used by intensive care units and anesthesiologists. It is relatively unique in its ability to provide sedation without causing respiratory depression. LIke clonidine, its mechanism of action is agonism of alpha-2 receptors in certain parts of the brain.