D-Lysergic acid N-(α-hydroxyethyl)amide

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D-lysergic acid α-hydroxyethylamide, also known as d-lysergic acid methyl carbinolamide, is a psychedelic alkaloid of the ergoline family, and occurs in various species of vines of the Convolvulaceae and some species of fungi.

Contents 1 Chemistry 2 Human Pharmacology 3 Effects 4 Legality 5 See also 6 External links

[edit] Chemistry

The chemical name for this alkaloid is 9,10-Didehydro-N-(1-hydroxyethyl)-6-methylergoline-8-carboxamide. Its structure is very similar to LSD in that the N,N-diethylamide group is replaced with an N-(1-hydroxyethyl)amide in d-lysergic acid α-hydroxyethylamide.

CAS# 3343-15-5

[edit] Human Pharmacology

While animal data involving d-lysergic acid α-hydroxyethylamide exists, the psysiological and pharmacological actions in humans is unknown. Animal studies do suggest the alkaloid may have some toxic effects at high levels.

[edit] Effects

The dominant entheogenic alkaloids in the seeds of Rivea corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian baby woodrose) and Ipomoea violacea (tlitliltzin) are ergine and isoergine (its epimer). However, neither is particularly hallucinogenic, but tend to produce sedative and narcotic effects. The human activity of d-lysergic acid α-hydroxyethylamide is unknown, but animal studies suggest it is an active psychededelic and hallucinogen and likely contributes to the seed's psychedelic and entheogenic activity. Dosage and duration of this compound is unknown.

[edit] Legality

D-lysergic acid α-hydroxyethylamide is unscheduled and uncontrolled in the United States, but possession and sales of it could be prosecuted under the Federal Analog Act because of its structural similarities to LSD and ergine. The legality of this drug, and other related substances, is under scrutiny as of July 2004, due to Operation Web Tryp.

[edit] See also

• Ergoline
• Ergot
• Lysergic acid
• Hallucinogenic drug
• Hawaiian baby woodrose (Argyreia nervosa)
• LSD
• Ololiuhqui (Rivea corymbosa)
• Tlitliltzin (Ipomoea violacea)

[edit] External links

• [http://research.lycaeum.org/researchpdfs/2343.pdf Ergot - A Rich Source of

Pharmacologically Active Substances] by Albert Hofmann

• Mixing the kykeon by P. Webster, D. M. Perrine & C.A.P. Ruck, a summary of human trials
• Erowid's LSA Vault

• Links to external chemical sources.

Ergolines edit
Lysergic acid derivatives
Bromocriptine, Cabergoline, Ergine, Ergonovine, Ergotamine, Lysergic acid, Lysergol, d-Lysergic acid hydroxyethylamide, Lisuride, Methergine, Methysergide, Pergolide
Hallucinogenic lysergamides
AL-LAD, ALD-52, BU-LAD, CYP-LAD, DAL, DAM-57, Ergonovine, ETH-LAD, LAE-32, LSD, LPD-824, LSM-775, Methylergonovine, MLD-41, PARGY-LAD, PRO-LAD
Other ergolines
Ergoline
Natural sources
Argyreia nervosa, Claviceps spp., Ipomoea tricolor, Ipomoea violacea, Rivea corymbosa