Talk:Cystic fibrosis transmembrane conductance regulator

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The online book Genes and Disease has it right. In most tissues, transport of chloride ions by the CFTR is followed by movement of sodium ions in the same direction. --JWSchmidt 02:22, 2 October 2006 (UTC)

In the article Non-specific activation of the epithelial sodium channel by the CFTR chloride channel Nagel et al conclude, "Electrochemical coupling predicts that activation of CFTR then leads to a change in membrane potential and increased Na+ conductance, as indeed found by Reddy et al. (1999)," and also, "activated CFTR must lead.....according to the Goldmann–Hodgkin–Katz equation (Hille, 1992), to a voltage-dependent sodium conductance."
--JWSchmidt 02:59, 2 October 2006 (UTC)

Thank you - sounds good to me. --Arcadian 03:00, 2 October 2006 (UTC)