Cryoglobulinemia
From Wikipedia, the free encyclopedia
ICD-10 | D89.1 |
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ICD-9 | 273.2 |
Cryoglobulinemia is the presence of high amount of heavy globulins (eg IgM) in the bloodstream which thicken or gel on exposure to cold (=cryoglobulins).
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[edit] Causes
These proteins may be present in mycoplasma pneumonia, multiple myeloma, certain leukemias, primary macroglobulinemia, and some autoimmune diseases, such as systemic lupus erythematosus and rheumatoid arthritis. This is also found occasionally as a symptom in 35% of chronic hepatitis C infections (Pascual et al 1990).
[edit] Reference
- Pascual M, Perrin L, Giostra E, Schifferli JA. Hepatitis C virus in patients with cryoglobulinemia type II. J Infect Dis 1990;162:569-570. PMID 2115556.