Craig plot
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The Craig plot is a plot of two substituent parameters (e.g. Hansch-Fujita p and Hammett σ values) used in rational drug design.
Two most used forms of a Craig plot are
- plotting the sigma constants of the Hammett equation versus hydrophobicity
- plotting the steric terms of the Taft equation against hydrophobicity
[edit] See also
[edit] References
- [IUPAC glossary|http://www.iupac.org/reports/1997/6905vandewaterbeemd/glossary.html]