Citrinin

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Citrinin is a mycotoxin which is produced by Aspergillus ochraceus, Penicillium citrinum, and related species, which contaminate grain. It causes mycotoxic nephropathy in livestock and has been implicated as a cause of Balkan nephropathy in humans.

Citrinin is used as a reagent in biological research. It induces mitochondrial permeability pore opening and inhibits respiration by interfering with complex I of the respiratory chain.

[edit] References

  • E.J. Da Lozzo et al. J. Biochem. Mol. Toxicol. 1998 12 291
  • G.M. Chagas et al. J. Appl. Toxicol. 1995 15 91

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