Chenodeoxycholic acid

From Wikipedia, the free encyclopedia

Chenodeoxycholic acid
Chenodeoxycholic acid
Systematic name chenodiol
3α,7α-dihydroxy-5β-cholanic acid
5β-cholanic acid-3α,7α-diol
Chemical formula C24H40O4
Molecular mass xx.xx g/mol
Density x.xxx g/cm3
Melting point 165-167 °C
Boiling point xx.x °C
CAS number [474-25-9]
SMILES C[C@@]34[C@] (CC[C@@H]4[C@@H]
(CCC(O)=O)C) ([H])[C@]2([H]) [C@H](O)C[C@]1
([H])C[C@H](O) CC[C@@](C)1 [C@]([H])2CC3
Disclaimer and references

Chenodeoxycholic acid is a bile acid, a white crystalline substance insoluble in water, with melting point at 165-167 °C. Its salts is called chenodeoxycholates. Chenodeoxycholic acid is one of the 4 main organic acids produced by the liver. It is soluble in alcohol and acetic acid.

Chenodeoxycholic acid is synthetized in the liver from cholesterol.

Chenodeoxycholic acid and cholic acid are the most important human bile acids. Some other mammals synthetize predominantly deoxycholic acid.

The Australian biotechnology company Giaconda has developed a treatment for Hepatitis C infection that combines chenodeoxycholic acid with bezafibrate.


[edit] External links